• Based on these preliminary clinical results with

  2019-04-30

  

  Based on these preliminary clinical results with low-dose, intermittent zoledronic acid, Hu et al. conducted a randomized phase II clinical study in order to clarify the role of metronomic low-dose zoledronic acid. Sixty breast cancer patients with bone metastases were randomized to receive either 1

• Introduction Dabigatran Boehringer Ingelheim Ingelheim Germa

  2019-04-30

  

  Introduction Dabigatran (Boehringer Ingelheim, Ingelheim, Germany) is a direct thrombin inhibitor, which can be orally administered, and is used to decrease the risk of ischemic stroke in patients with non-valvular atrial fibrillation (NVAF). In early phase studies of dabigatran in healthy men, cet

• The goals of Vision the global initiative

  2019-04-30

  

  The goals of Vision 2020—the global initiative to eliminate avoidable blindness by 2020—include increasing cataract surgical rate and cataract surgical coverage. However, quality must not be sacrificed for quantity. The final visual outcome matters, both to the individual patient and to the communit

• br The Medical Education Partnership Initiative MEPI is

  2019-04-30

  

  The Medical Education Partnership Initiative (MEPI) is an innovative and potentially transformative 5-year programme, established by the US Government in 2010, to increase the number of doctors to meet crucial human resource needs in sub-Saharan Africa. MEPI allows African institutions that BQ-78

• Additionally new resistance in a

  2019-04-30

  

  Additionally, new resistance in a pathogenic bacterium with no treatment options should be notifiable under International Health Regulations to relevant authorities and control measures must be implemented without delay. This approach will work only if the new systems developing across the world, b

• br Conflict of interests br

  2019-04-29

  

  Conflict of interests Chronic lymphocytic leukemia (CLL) is the most frequent hematologic neoplasm in Western countries. The clinical course of chronic lymphocytic leukemia ranges from a very indolent disorder with a normal lifespan, to a rapidly progressive disease leading to death. The variab

• br Last autumn the image of a young http

  2019-04-29

  

  Last autumn the image of a young Syrian boy lying dead on a Turkish beach highlighted the humanitarian plight of refugees and influenced public opinion. The photograph of Alan Kurdi spoke to people more powerfully than any words could have done. Photographs can move us, enrage us, challenge our id

• br Metabolic stress Glycolysis accounts for less than of

  2019-04-29

  

  Metabolic stress Glycolysis accounts for less than 5% of total cellular ATP production in the beating heart under aerobic conditions. However, studies of isolated cardiac myocytes have shown that cardiac stress induced by selectively inhibiting glycolytic ATP production can lead to electromechani

• Newer methods for assessing bone quality are under

  2019-04-29

  

  Newer methods for assessing bone quality are under investigation, such as microindentation technique and high-resolution peripheral quantitative CT [23–25], but are regarded as exploratory. High resolution-peripheral quantitative CT appears to be better than DEXA at predicting fracture risk, but has

• Pellicer alude a esta leyenda varias veces en Oda

  2019-04-29

  

  Pellicer alude akt pathway esta leyenda varias veces en “Oda a Cuauhtémoc”, con imágenes que sugieren la batalla con un astro, la estrella de la aurora de Quetzalcóatl, que en el poema representa un destino fatal: “El arco negro se tendió ante la aurora / y en el último astro fue a clavarse la flech

• With the publication of this month s issue we

  2019-04-29

  

  With the publication of this month\'s issue, we mark \'s first birthday. I hope you will allow me to effuse for a moment in the manner of a new parent discovering the fascination of her offspring\'s everyday achievements… Since its conception in March, 2013, the infant has maintained a healthy inta

• Regarding therapy management the cases in this study were

  2019-04-29

  

  Regarding therapy management, the cases in this study were treated with CHOP (cyclophosphamide, doxorubicin, vincristine and prednisolone) or CHOP-like regimens as first-line therapy. The 5-year overall survival (OS) rate has been reported to be 7% [3]. Cases 2–4 in fact had faint responses, and the

• Sobhy and colleagues study emphasises the relative

  2019-04-29

  

  Sobhy and colleagues\' study emphasises the relative safety of spinal anaesthesia when compared with general anaesthesia. When all goes well, spinal anaesthesia is the most straightforward anaesthetic technique for caesarean delivery. But occasionally spinal anaesthesia can lead to disaster. The Sou

• According to several cases earlier reported by

  2019-04-28

  

  According to several cases earlier reported by Gandhi et al, the median time of acute pancreatitis occurring is 12 days (range: 9–16 days), from the last administration of BV, and most events occurred in the first course of BV treatment. One patient experienced recurrent pancreatitis in the fifth co

• La carta de Carlos Fuentes y la publicaci n

  2019-04-28

  

  La carta de Carlos Fuentes y la publicación Immunology Inflammation Compound Library la que fue dirigida, representan testimonios de auténtica colaboración entre autores de distintas generaciones y de diferentes ámbitos. Un esfuerzo colectivo y espontáneo en torno a la literatura que permite evocar

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