• So far GnRH receptors have been detected in

  2022-04-14

  

  So far, GnRH receptors have been detected in the human ovary, but their physiological importance is still unclear (). In particular, GnRH receptors as well as GnRH types I and II have been localized in the granulosa CGP 53353 of pre-ovulatory follicles, but not of follicles from the primordial to th

• Ning et al showed that LPC appeared to

  2022-04-14

  

  Ning et al. showed that LPC 18:1 appeared to increase insulin release through both GPR119-dependent and -independent mechanisms (Ning et al., 2008). In our study, we have shown that not only GPR119 but also GPR40 and GPR55 participate in LPC-stimulated insulin secretion (Fig. 4, Fig. 5) and target p

• br Materials and methods br Results br

  2022-04-14

  

  Materials and methods Results Discussion In this study, we discover that Sufu stabilizes Gli1 protein levels by antagonizing Numb/Itch-mediated protein degradation. Together with previous work that demonstrates control of Gli2/3 protein levels by Sufu (Chen et al., 2009, Jia et al., 2009, W

• The Growth Hormone Secretagogue Receptor GHSR also known as

  2022-04-14

  

  The Growth Hormone Secretagogue Receptor (GHSR), also known as the ghrelin receptor, is a G protein-coupled receptor (GPCR) expressed widely throughout the body and brain, with particular enrichment in AZD1480 regions concerned with homeostatic and motivational function such as the hypothalamus, hi

• br Ghrelin actions in the central nervous

  2022-04-14

  

  Ghrelin actions in the central nervous system Ghrelin induces thymopoeisis GHS-R1a is expressed in immune cells, including thymocytes and T-cells [13]. Infusion of ghrelin increases the number of thymocytes and thymus size in 14-, 20-, and 24-month-old mice, and with decreased thymic adiposity

• The patterns of Fig Fig emerge at

  2022-04-14

  

  The patterns of Fig. 1, Fig. 2 emerge at the multicellular level; their dynamics can only be understood by integrating different magnitudes and feedback loops in networks incorporating the coupling between biochemical and bioelectrical signals (see Fig. 6, Fig. 8). Interestingly, this might also be

• Two types of processes intrinsic and

  2022-04-13

  

  Two types of processes, intrinsic and extrinsic, contribute synergistically to the age-related change on structural integrity and physiological function of the skin (Farage, Miller, Elsner, & Maibach, 2008). Intrinsic aging arise from genetically programmed cell aging, normal metabolic activities, a

• br Conclusions Histone acetylation deacetylation is

  2022-04-13

  

  Conclusions Histone acetylation/deacetylation is a major epigenetic mechanism implicated in the regulation of transcription and various biological processes such as development and gametogenesis from plants to vertebrates. However, despite being well characterized in zebrafish, acetyltransferase

• tcy It is important to note that histamine

  2022-04-13

  

  It is important to note that histamine H1 and H2 receptors are coupled to different G proteins and that their crossinterference induced by histamine H1 and H2 receptor inverse agonists depends on the cointernalization mechanism. To date, histamine H1 and H2 receptor inverse agonist have shown to int

• Nogo-66 (1-40) sale Almost all of the series and compounds e

  2022-04-13

  

  Almost all of the series and compounds exhibited higher activities compared with the compounds in the other series. In these series, the tetrazole group was directly linked to a nitrogen atom of the amide group at the C-28 position, and the C-3 hydroxy group was either unmodified, oxidized, esterifi

• br Introduction Adenosine triphosphate ATP is an organic

  2022-04-13

  

  Introduction Adenosine-5′-triphosphate (ATP) is an organic molecule (nucleoside triphosphate) which consists of adenine, ribose, and three phosphoric Betamethasone Dipropionate residues. ATP serves as a temporary carrier of energy in all living cells, so it is a common substance in any organism.

• br Pathophysiology of glaucoma Glaucoma is a group of

  2022-04-12

  

  Pathophysiology of glaucoma Glaucoma is a group of optic neuropathies defined by progressive degeneration of RGCs and their FG2216 in the optic nerve, which leads to irreversible loss of vision [3,8,9]. RGC degeneration is often significantly advanced before changes in visual acuity and evidence

• The ability of FFA to elevate intracellular levels of

  2022-04-12

  

  The ability of FFA4 to elevate intracellular levels of Ca2+5, 38, 39, 40 provided early predictions of a key role of the phosphoinositidase C-linked G proteins Gq and/or G11 in transduction of signals from this receptor, while later studies that examined production of inositol phosphates [41] provid

• We also investigated fat depots in mesenteric and retroperit

  2022-04-12

  

  We also investigated fat depots in mesenteric and retroperitoneal adipose tissues as well as in the liver and verified a reduction in lipid droplets following exercise or exercise and FS oil treatments in the liver from obese mice. Potential molecular candidates in the modulation of adipose tissue b

• Acknowledgments This research was supported

  2022-04-12

  

  Acknowledgments This research was supported by the Korea Research Institute of Chemical Technology (KRICT) funded by the Ministry of Science, ICT & Future Planning (KK1703-G00, KK1707-C05, SI1707-02, KK-1607-C09, and SKO1707C05) and a grant of the Korea Health Technology R&D Project through the Kor

15570 records 444/1038 page Previous Next First page 上5页 441442443444445 下5页 Last page