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RHA is an agricultural by
2020-04-15
RHA is an agricultural by-product obtained from the burning process of rice hull [7], [8]. Rice hull is the outer layer of paddy grain. About 20% of rice hull converts into RHA when it is burnt during the Illumina for 1 ng DNA generation processes [8], [9]. If RHA produced at less than 700 °C, it c
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In a larger study of
2020-04-15
In a larger study of 22 patients with nondiabetic proteinuric chronic kidney disease, BQ-123 produced significant natriuresis, resulting from increased renal blood flow. In addition, ETA antagonism reduced blood pressure and proteinuria, and, a new finding, decreased arterial stiffness. However, in
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The idea that ASB can drive
2020-04-14
The idea that ASB11 can drive compartment expansion in the CNS is further supported by in vitro work in human neuronal precursors. Nerve growth factor (NGF)-induced differentiation of PC12 pheochromocytoma Netilmicin Sulfate receptor [11] and RA-induced human pluripotent teratocarcinoma carcinoma (N
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br Transparency document br Main Text The centrosome is
2020-04-14
Transparency document Main Text The centrosome is a non-membrane-bound organelle found in most animal cells. It has several important functions, including control of cilia formation, microtubule organization and nucleation, spindle assembly and transport of organelles and vesicles. Centrosomes
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Enzymatic assay The usual in vitro test
2020-04-14
Enzymatic assay. The usual in vitro test for the measure of the activity of DbH involves ascorbate as a cosubstrate (e.g., 5mM) and tyramine as a substrate (e.g., 10mM). When using N-aryl-N′-hydroxyguanidines instead of ascorbate, the hydroxylase activity of DbH was measured by HPLC as the amounts o
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If the effects described here are present in
2020-04-14
If the effects described here are present in catalysis, their empirical confirmation poses many challenges. Cat state correlations are fragile outside an environment especially suited for their preservation. As present day observational techniques whether in vivo or in vitro were not designed bearin
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br Conflict of interest statement br Introduction Endothelin
2020-04-14
Conflict of interest statement Introduction Endothelins (ETs) are a family of multifunctional, naturally occurring peptides with long-lasting vasoconstrictor and pressor effects (Zhou et al., 2004). They are synthesized as a large protein, the pre-proET-1 or Big ET-1, which is subsequently cle
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The expression of EBI has been found
2020-04-14
The expression of EBI2 has been found to be dysregulated in several types of B cell malignancies and is thus reduced in e.g. diffuse large B-cell lymphomas [12] and chronic lymphocytic leukemia [13] and increased in post-transplantation lymphoproliferative disorders (PTLDs) [14]. EBI2 is also highly
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Dgat mice however had less adipose tissue as reflected by
2020-04-14
Dgat−/− mice, however, had less adipose tissue, as reflected by lower total fat pad weights and body triglyceride content. Because of these findings, we hypothesized that, although Dgat−/− mice could make triglycerides through non-DGAT pathway(s), their triglyceride synthesis capacity might not be e
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br Introduction Acylglycerol acyltransferases AGATs
2020-04-14
Introduction Acylglycerol acyltransferases (AGATs) are predominantly responsible for triglyceride synthesis in the body, via two major pathways: the glycerol phosphate (GP) pathway (Kennedy, 1957) and the monoacylglycerol (MG) pathway (see Coleman and Lee, 2004, Yen et al., 2008). The final step
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br Conclusion Our objective is to promote cell activity
2020-04-14
Conclusion Our objective is to promote cell activity on biomaterials, especially for use in regenerative medicine, by grafting THPs containing collagen-binding sites onto inert substrates. We have previously reported a methodology to derivatize EDC/NHS crosslinked films with photoreactive THPs. T
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In previous works Gotor Vila et al c
2020-04-14
In previous works (Gotor-Vila et al., 2017c), differences in solubility between the two carriers used during formulation were evidenced. Summarizing, maltodextrin (BA3 product) resulted in a much more soluble product since this polysaccharide is typically composed of an amount of reducing sugars bet
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Many PIM inhibitors have been reported to date however
2020-04-14
Many PIM inhibitors have been reported to date [7], [8], [9] however, none of them has been marketed so far. SGI-1776 is a representative first-generation PIM inhibitor, which had been under clinical trials for leukemia and prostate cancer [10]. While most of the first-generation PIM inhibitors are
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We hypothesize that both IGF dependent kinase activation and
2020-04-14
We hypothesize that both IGF-1-dependent kinase activation and locally synthesized neuroestrogens interactively regulate estrogen receptor activity in neuronal Q-VD(OMe)-OPh receptor in the absence of exogenously applied estradiol. The Neuro-2A cell line was chosen as the model system for these stu
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CPG a metalloenzyme derived from sp was the
2020-04-13
CPG2, a metalloenzyme derived from sp., was the elected enzyme for the first pilot-scale clinical trial of ADEPT. This enzyme has no mammalian homologue and activates glutamic Metoprolol Succinate prodrug derivatives of several nitrogen mustards alkylating agents., , , , , A bond cleavable by CPG
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